All twenty-one, and what can be said about each

Transcribed from the label artwork. No typed ingredient list was supplied and none has been invented.

The panel

Supplement Facts, as printed

Serving Size: 1 ml · Servings Per Container: 30

Supplement Facts as printed on the Hawaiian Harmony label
Ingredient	Amount Per Serving	% Daily Value
Calories	0
Chromium (as Chromium Picolinate)	7 mcg	20%*
Proprietary Blend	15.47 mg	†

Maca Root Extract (Lepidium meyenii)^, African Mango Seed Extract (Irvingia gabonensis)", Grape Seed Extract (Vitis vinifera)^, Guarana Seed Extract (Paullinia cupana)^, Eleuthero Root Extract (Eleutherococcus senticosus)^, Astragalus Root Extract (Astragalus membranaceus)^, Green Tea Leaf Extract^, Gymnema Leaf Extract (Gymnema sylvestre)^, Forskohlii Root Extract (Coleus forskohlii)^, Cayenne Pepper Fruit Extract (Capsicum annuum)^, Grapefruit Seed (Citrus paradisi)^, Ginseng Root Extract (Panax ginseng), Raspberry Ketones, L-glutamine, L-Tyrosine, L-Arginine, Beta Alanine, Monoammonium Glycyrrhizinate, GABA (Gamma Aminobutyric Acid), L-Tryptophan, L-Carnitine HCl.

Not a significant source of saturated fat, trans fat, cholesterol, sodium, dietary fiber, total sugars, added sugars, protein, Vitamin D, calcium, iron, or potassium.
* Percent Daily Value (DV) are based on a 2,000 calorie diet.
† Daily Value (DV) not established.
^ Sourced from a concentrate with a 20:1 extract equivalent.
" Sourced from a concentrate with a 10:1 extract equivalent.

Other Ingredients: Water, Natural flavors, Potassium Sorbate, Stevia, Xylitol, Citrus Extract.

The same panel, worked out

The same panel, with the arithmetic finished
As printed	Against what	Works out to
Chromium 7 mcg	FDA Daily Value, 35 mcg	20% of the Daily Value. The label's own figure, and it is right.
Chromium 7 mcg	Adequate Intake, 35 mcg for a man 19–50	one fifth of a day's intake. Food supplies the rest.
Chromium 7 mcg	chromium-only supplements, 200–500 mcg	between 1.4% and 3.5% of what a chromium supplement usually carries.
as Chromium Picolinate	about 1.2% absorbed from picolinate	roughly 0.08 mcg absorbed — eighty nanograms.
Proprietary Blend 15.47 mg	the twenty-one names under it	0.74 mg each if they were equal, and nothing says they are.
Proprietary Blend 15.47 mg	everything the panel declares	99.95% of the declared weight is on this one line.
^ 20:1 extract equivalent	15.47 mg of concentrate	at most 309.4 mg of starting plant material, shared out among twenty-one names.

Transcribed from the label artwork supplied with this product. No typed panel was supplied and none has been invented.

The staircase

Every position, and the most the name in it can weigh.

Twenty-one names, one weight15.47 mg total · descending order · 15.47 ÷ k

1. Maca Root Extract Lepidium meyenii 20:1 concentrate
Ceiling here: ≤ 15.47 mg · 15.47 ÷ 1. 1.03% of the smallest published daily amount, 1500 mg.
Trials of sexual function used 1.5 to 3 g a day of gelatinised maca root; 1,500 mg was reported not effective and 3,000 mg effective in one SSRI-related trial.
2. African Mango Seed Extract Irvingia gabonensis 10:1 concentrate
Ceiling here: ≤ 7.74 mg · 15.47 ÷ 2. No daily amount was found for this ingredient in a source this site opened, so none is printed.
3. Grape Seed Extract Vitis vinifera 20:1 concentrate
Ceiling here: ≤ 5.16 mg · 15.47 ÷ 3. 3.44% of the smallest published daily amount, 150 mg.
Oral doses of 150 to 2,000 mg a day over 2 to 24 weeks — for grape seed extract, which is what this label prints.
4. Guarana Seed Extract Paullinia cupana 20:1 concentrate
Ceiling here: ≤ 3.87 mg · 15.47 ÷ 4. 5.16% of the smallest published daily amount, 75 mg.
“Doses ranging from 75 mg to 1,000 mg daily have been used in limited clinical trials evaluating stimulant effects.” Guarana seed is 3% to more than 5% caffeine by dry weight, against 1% to 2% for a coffee bean.
5. Eleuthero Root Extract Eleutherococcus senticosus 20:1 concentrate
Ceiling here: ≤ 3.09 mg · 15.47 ÷ 5. No daily amount was found for this ingredient in a source this site opened, so none is printed.
6. Astragalus Root Extract Astragalus membranaceus 20:1 concentrate
Ceiling here: ≤ 2.58 mg · 15.47 ÷ 6. No published daily amount to compare against.
The monograph is explicit: “Clinical trial data are lacking to guide dosing recommendations for A. membranaceus products.” There is no published amount to compare this one against.
7. Green Tea Leaf Extract 20:1 concentrate
Ceiling here: ≤ 2.21 mg · 15.47 ÷ 7. 2.63% of the smallest published daily amount, 84 mg.
An EGCG range of 84 to 386 mg a day is identified for diabetes support; catechins or extract at 160 to 2,488 mg a day in cardiovascular work.
8. Gymnema Leaf Extract Gymnema sylvestre 20:1 concentrate
Ceiling here: ≤ 1.93 mg · 15.47 ÷ 8. 0.97% of the smallest published daily amount, 200 mg.
“Clinical studies investigating antidiabetic effects have typically used 200 or 400 mg extract daily standardized to contain 25% gymnemic acids”; 500 to 1,000 mg a day of leaf extract in diabetes trials.
9. Forskohlii Root Extract Coleus forskohlii 20:1 concentrate
Ceiling here: ≤ 1.72 mg · 15.47 ÷ 9. 17.19% of the smallest published daily amount, 10 mg.
“Oral forskolin has been studied using 10 mg daily over 2 to 6 months” for asthma; 250 mg of a 10% extract twice daily in obesity work.
10. Cayenne Pepper Fruit Extract Capsicum annuum 20:1 concentrate
Ceiling here: ≤ 1.55 mg · 15.47 ÷ 10. No daily amount was found for this ingredient in a source this site opened, so none is printed.
11. Grapefruit Seed Citrus paradisi 20:1 concentrate
Ceiling here: ≤ 1.41 mg · 15.47 ÷ 11. No daily amount was found for this ingredient in a source this site opened, so none is printed.
12. Ginseng Root Extract Panax ginseng
Ceiling here: ≤ 1.29 mg · 15.47 ÷ 12. 1.29% of the smallest published daily amount, 100 mg.
“the dose of extracts has generally ranged from 100 to 400 mg”, and crude root from 0.5 to 3 g a day. Glucose results are reported in some studies and not others.
13. Raspberry Ketones
Ceiling here: ≤ 1.19 mg · 15.47 ÷ 13. No daily amount was found for this ingredient in a source this site opened, so none is printed.
14. L-glutamine
Ceiling here: ≤ 1.1 mg · 15.47 ÷ 14. 0.01% of the smallest published daily amount, 21000 mg.
One study used 0.3 g per kg of body weight — about 21 g for a 70 kg adult — and another almost 45 g a day. ODS concludes the research does not support glutamine alone for improving exercise performance.
15. L-Tyrosine
Ceiling here: ≤ 1.03 mg · 15.47 ÷ 15. No daily amount was found for this ingredient in a source this site opened, so none is printed.
16. L-Arginine
Ceiling here: ≤ 0.97 mg · 15.47 ÷ 16. 0.05% of the smallest published daily amount, 2000 mg.
“2–20 g/day arginine”, most commonly 2 to 10 g as a single dose. ODS reports it “provided little or no enhancement of athletic performance”.
17. Beta Alanine
Ceiling here: ≤ 0.91 mg · 15.47 ÷ 17. 0.06% of the smallest published daily amount, 1600 mg.
“1.6–6.4 g/day” over 4 to 8 weeks; the ISSN recommends 4 to 6 g a day in divided doses.
18. Monoammonium Glycyrrhizinate
Ceiling here: ≤ 0.86 mg · 15.47 ÷ 18. No published daily amount to compare against.
Not a dose but a limit: the suggested acceptable daily intake for glycyrrhizin is 0.2 mg per kg of body weight — about 14 mg for a 70 kg adult. This ingredient is eighteenth of twenty-one, so it weighs at most 0.86 mg. It is comfortably under.
19. GABA (Gamma Aminobutyric Acid)
Ceiling here: ≤ 0.81 mg · 15.47 ÷ 19. No daily amount was found for this ingredient in a source this site opened, so none is printed.
20. L-Tryptophan
Ceiling here: ≤ 0.77 mg · 15.47 ÷ 20. No daily amount was found for this ingredient in a source this site opened, so none is printed.
21. L-Carnitine HCl
Ceiling here: ≤ 0.74 mg · 15.47 ÷ 21. 0.07% of the smallest published daily amount, 1000 mg.
1 to 4 g a day in athletic-performance studies. Supplemental L-carnitine is absorbed at about 14% to 18%, against 63% to 75% for the carnitine in food.

The first name can be anything up to the whole 15.47 mg. The twenty-first cannot be more than 0.74 mg — 737 micrograms. If all twenty-one were equal they would be 0.74 mg each.

The eleven with a published dose

Ceiling against the smallest published dose11 of 21 have one · 0 reach it

Forskohlii Root Extract17.19% of it
10 mg published
≤ 1.72 mg here, at position 9 of 21. “Oral forskolin has been studied using 10 mg daily over 2 to 6 months” for asthma; 250 mg of a 10% extract twice daily in obesity work.
Guarana Seed Extract5.16% of it
75 mg published
≤ 3.87 mg here, at position 4 of 21. “Doses ranging from 75 mg to 1,000 mg daily have been used in limited clinical trials evaluating stimulant effects.” Guarana seed is 3% to more than 5% caffeine by dry weight, against 1% to 2% for a coffee bean.
Grape Seed Extract3.44% of it
150 mg published
≤ 5.16 mg here, at position 3 of 21. Oral doses of 150 to 2,000 mg a day over 2 to 24 weeks — for grape seed extract, which is what this label prints.
Green Tea Leaf Extract2.63% of it
84 mg published
≤ 2.21 mg here, at position 7 of 21. An EGCG range of 84 to 386 mg a day is identified for diabetes support; catechins or extract at 160 to 2,488 mg a day in cardiovascular work.
Ginseng Root Extract1.29% of it
100 mg published
≤ 1.29 mg here, at position 12 of 21. “the dose of extracts has generally ranged from 100 to 400 mg”, and crude root from 0.5 to 3 g a day. Glucose results are reported in some studies and not others.
Maca Root Extract1.03% of it
1500 mg published
≤ 15.47 mg here, at position 1 of 21. Trials of sexual function used 1.5 to 3 g a day of gelatinised maca root; 1,500 mg was reported not effective and 3,000 mg effective in one SSRI-related trial.
Gymnema Leaf Extract0.97% of it
200 mg published
≤ 1.93 mg here, at position 8 of 21. “Clinical studies investigating antidiabetic effects have typically used 200 or 400 mg extract daily standardized to contain 25% gymnemic acids”; 500 to 1,000 mg a day of leaf extract in diabetes trials.
L-Carnitine HCl0.07% of it
1000 mg published
≤ 0.74 mg here, at position 21 of 21. 1 to 4 g a day in athletic-performance studies. Supplemental L-carnitine is absorbed at about 14% to 18%, against 63% to 75% for the carnitine in food.
Beta Alanine0.06% of it
1600 mg published
≤ 0.91 mg here, at position 17 of 21. “1.6–6.4 g/day” over 4 to 8 weeks; the ISSN recommends 4 to 6 g a day in divided doses.
L-Arginine0.05% of it
2000 mg published
≤ 0.97 mg here, at position 16 of 21. “2–20 g/day arginine”, most commonly 2 to 10 g as a single dose. ODS reports it “provided little or no enhancement of athletic performance”.
L-glutamine0.01% of it
21000 mg published
≤ 1.1 mg here, at position 14 of 21. One study used 0.3 g per kg of body weight — about 21 g for a 70 kg adult — and another almost 45 g a day. ODS concludes the research does not support glutamine alone for improving exercise performance.

Every bar above is drawn at least a hair wide so it can be seen. Four of the eleven are under a tenth of one per cent, and the widest — forskohlii, against a 10 mg asthma dose that is the smallest figure in this whole table — is 17%.

The ten without one

African Mango Seed Extractposition 2 · ≤ 7.74 mg
No daily amount for this ingredient was found in a source this site could open and read in full. Rather than reach for a figure, this site says so.
Eleuthero Root Extractposition 5 · ≤ 3.09 mg
No daily amount for this ingredient was found in a source this site could open and read in full. Rather than reach for a figure, this site says so.
Astragalus Root Extractposition 6 · ≤ 2.58 mg
The monograph is explicit: “Clinical trial data are lacking to guide dosing recommendations for A. membranaceus products.” There is no published amount to compare this one against.
Cayenne Pepper Fruit Extractposition 10 · ≤ 1.55 mg
No daily amount for this ingredient was found in a source this site could open and read in full. Rather than reach for a figure, this site says so.
Grapefruit Seedposition 11 · ≤ 1.41 mg
No daily amount for this ingredient was found in a source this site could open and read in full. Rather than reach for a figure, this site says so.
Raspberry Ketonesposition 13 · ≤ 1.19 mg
No daily amount for this ingredient was found in a source this site could open and read in full. Rather than reach for a figure, this site says so.
L-Tyrosineposition 15 · ≤ 1.03 mg
No daily amount for this ingredient was found in a source this site could open and read in full. Rather than reach for a figure, this site says so.
Monoammonium Glycyrrhizinateposition 18 · ≤ 0.86 mg
Not a dose but a limit: the suggested acceptable daily intake for glycyrrhizin is 0.2 mg per kg of body weight — about 14 mg for a 70 kg adult. This ingredient is eighteenth of twenty-one, so it weighs at most 0.86 mg. It is comfortably under.
GABA (Gamma Aminobutyric Acid)position 19 · ≤ 0.81 mg
No daily amount for this ingredient was found in a source this site could open and read in full. Rather than reach for a figure, this site says so.
L-Tryptophanposition 20 · ≤ 0.77 mg
No daily amount for this ingredient was found in a source this site could open and read in full. Rather than reach for a figure, this site says so.

What the 20:1 buys you

15.47 mgof concentrate, all twenty-one names together

309.4 mgof starting plant, at the label's own 20:1 ratio

Ten of the twenty-one names carry ^ and one carries ". The footnotes say those are 20:1 and 10:1 concentrates. Read the ratio in the buyer's favour — assume every milligram is 20:1 — and the whole blend represents 309.4 mg of plant material, shared among twenty-one ingredients. One studied dose of maca alone is 1,500 mg.

The ratio also cuts the other way, and the label does not settle it: a 20:1 concentrate is concentrated in something, and without a marker compound or a standardisation percentage there is no way to know in what.

Chromium

The one amount the label declares7 mcg · 20% of the Daily Value · correct

This label7 mcg
Adequate Intake, adult man 19–5035 mcg
A multivitamin35–120 mcg
A chromium supplement200–500 mcg

20%of the 35 mcg Daily Value. The label's arithmetic is right.

1.4–3.5%of the 200–500 mcg a chromium-only supplement usually carries.

0.084 mcgabsorbed, at the 1.2% figure published for chromium picolinate.

Two things are true at once here and this site prints both. 7 mcg is inside the range of doses that have been studied — trials have run from 1.28 to 1,000 mcg a day — so nobody can call it an impossible amount. And NIH's own conclusion across that whole literature is that there is “insufficient rationale to recommend chromium supplements for people with type 2 diabetes”, at any dose in it. No Tolerable Upper Intake Level has been set for chromium.

The inactive ingredients

Water: The carrier. This is a liquid supplement, and the 15.47 mg is suspended in it — which is why the label's first instruction is to shake it.
Natural flavors: A category, not an ingredient. Unquantified by design.
Potassium Sorbate: A preservative.
Stevia: A sweetener.
Xylitol: A sugar alcohol used as a sweetener. Safe for people at these amounts and dangerous to dogs at small ones — see the note below.
Citrus Extract: Listed among the inactives rather than in the blend. Note that Grapefruit Seed appears separately inside the blend.

What is not on this label

The split inside the 15.47 mg blend
No individual amount is given for any of the twenty-one names. 21 CFR 101.36(c) permits this. It does not make the amounts knowable.
Standardisation for any botanical
Ten names carry a 20:1 concentrate marker and one a 10:1. None carries a marker compound or a percentage — no gymnemic acid content, no EGCG content, no ginsenoside content — so the extract weight cannot be converted into an amount of anything active.
How much caffeine is in it
Guarana seed is 3% to more than 5% caffeine by dry weight. Guarana is fourth of twenty-one, so its ceiling is 3.87 mg, but no caffeine content is declared and the panel has no caffeine line.
How much xylitol is in it
Xylitol is in the Other Ingredients list, which is unquantified by design. It is worth knowing about in a household with a dog.
A certificate of analysis
A CoA reference is printed. The document was not supplied to this site, so nothing here treats it as a test result.
A sales phone number
The written pack reports none on the sales or contact pages. The bottle prints one, and this site publishes it.
Shipping cost and delivery estimate
Neither was supplied, so neither is printed.
Any customer rating this site can stand behind
Review figures were supplied. They are published as layout copy, with their own arithmetic checked, and are marked up as reviews nowhere.
Who manufactures it
The label names a distributor and states that the product was made in an FDA registered facility. It does not name the facility.

Nine things this site would print if they had been supplied. Each is written here rather than filled in, because a plausible number in one of these slots would be worth less than the empty slot.

Sources

Chromium — Fact Sheet for Health ProfessionalsNIH Office of Dietary SupplementsDaily Value 35 mcg; Adequate Intake 35 mcg for men and 25 mcg for women aged 19–50; chromium-only supplements typically provide 200–500 mcg; diabetes trials used 1.28 to 1,000 mcg daily, most often as picolinate; about 1.2% of chromium is absorbed from chromium picolinate; no Tolerable Upper Intake Level was established; there is “insufficient rationale to recommend chromium supplements for people with type 2 diabetes.”
Dietary Supplements for Exercise and Athletic PerformanceNIH Office of Dietary SupplementsBeta-alanine 1.6–6.4 g a day; arginine 2–20 g a day, which “provided little or no enhancement of athletic performance”; glutamine at 0.3 g per kg of body weight and up to almost 45 g a day; little support for ginseng in athletic performance.
Carnitine — Fact Sheet for Health ProfessionalsNIH Office of Dietary Supplements1 to 4 g a day in athletic-performance studies; supplemental L-carnitine bioavailability about 14% to 18% against 63% to 75% for dietary carnitine.
Dietary Supplement Labeling Guide, Chapter IV: Nutrition LabelingU.S. Food and Drug AdministrationBlend ingredients must be listed “in descending order of predominance by weight” with the blend's total weight on the same line; ingredients with an RDI or DRV must be listed separately with their individual weights declared. 21 CFR 101.36(b)(2) and (c).
Paws Off Xylitol; It's Dangerous for DogsU.S. Food and Drug AdministrationXylitol appears in many products including dietary supplements; in dogs it “may result in a potent release of insulin” and “a rapid and profound decrease in the level of blood sugar” within 10 to 60 minutes. FDA advises checking labels and keeping such products out of reach.
Gymnema — clinical monographDrugs.com natural products database“Clinical studies investigating antidiabetic effects have typically used 200 or 400 mg extract daily standardized to contain 25% gymnemic acids”; 500 to 1,000 mg a day of leaf extract in diabetes trials; “Few methodologically sound clinical studies exist.”
Green Tea — clinical monographDrugs.com natural products databaseCatechins or extract at 160 to 2,488 mg a day; an EGCG range of 84 to 386 mg a day for diabetes support; green tea extract should not be taken on an empty stomach because plasma EGCG rises fivefold in the fasted state.
Guarana — clinical monographDrugs.com natural products database“Doses ranging from 75 mg to 1,000 mg daily have been used in limited clinical trials”; guarana seed is 3% to greater than 5% caffeine by dry weight against approximately 1% to 2% for coffee beans.
Ginseng — clinical monographDrugs.com natural products databaseCrude root 0.5 to 3 g a day; “the dose of extracts has generally ranged from 100 to 400 mg”; glucose improvements reported in some studies but not others.
Forskolin — clinical monographDrugs.com natural products database“Oral forskolin has been studied using 10 mg daily over 2 to 6 months”; 250 mg of a 10% forskolin extract twice daily for 12 weeks in obesity work.
Maca — clinical monographDrugs.com natural products database1.5 to 3 g a day of gelatinised maca root over 12 weeks; 1,500 mg reported not effective and 3,000 mg effective in one SSRI-related trial.
Grape Seed — clinical monographDrugs.com natural products databaseOral doses of 150 to 2,000 mg a day over 2 to 24 weeks.
Astragalus — clinical monographDrugs.com natural products database“Clinical trial data are lacking to guide dosing recommendations for A. membranaceus products.”
Licorice — clinical monographDrugs.com natural products database“The acceptable daily intake (ADI) for glycyrrhizin is suggested to be 0.2 mg/kg/day”, with a proposed no-observed-effects level of 2 mg/kg/day; mineralocorticoid hypertension has been produced by as little as 50 g a day of licorice.