Hawaiian Harmony Interactions: Caffeine, Chromium, Licorice and Your Home
When people look up Hawaiian Harmony interactions they often mean medicines, but interactions are wider than that. Food, drinks, other supplements and even the family dog can all matter. This post covers the ones this site can check, and says which need a professional.
Written by the Hawaiianzharmony editorial desk · Medically reviewed by Dr. Maria Menucci, Physician · Last updated
Hawaiian Harmony interactions you can check yourself are few. Guarana and green tea add caffeine in an undeclared amount. Chromium can add up with a multivitamin. A licorice compound is named. Xylitol is a risk to dogs. Because no blend amounts are printed, medicine interactions need a pharmacist.

Key facts
- Guarana and green tea are caffeine sources. No caffeine amount is declared.
- A multivitamin has 35 to 120 mcg of chromium and a chromium supplement 200 to 500 mcg, against 7 mcg here.
- A licorice compound, monoammonium glycyrrhizinate, is 18th of 21 names, so it weighs at most 0.86 mg.
- Green tea extract should not be taken on an empty stomach, because blood levels of its catechin rise fivefold when fasted.
- Xylitol is dangerous to dogs. Keep the bottle out of reach.
- Medicine interactions cannot be checked against a dose, because no blend amounts are printed.
Which Hawaiian Harmony interactions involve caffeine?
The blend names guarana seed extract and green tea leaf extract. Both are caffeine sources. Guarana seed is 3% to more than 5% caffeine by dry weight, against 1% to 2% for a coffee bean.
That sounds like a lot, but the weights are small. Guarana is 4th of 21 names, so it weighs at most 3.87 mg. Green tea is 7th, at most 2.21 mg. No caffeine line appears on the panel, so nobody outside the company can say how much caffeine a dropperful holds.
What does that mean in a day? If you already drink coffee, tea or energy drinks, the drops add some caffeine to a total you already know. If you are very sensitive, if you sleep badly after any caffeine, or if you have been told to avoid it, say so to your doctor. A cautious step is to take the drops earlier in the day.
Can Hawaiian Harmony interactions come from other chromium products?
Yes, by simple adding. Chromium is the one declared amount: 7 mcg as chromium picolinate, 20% of the 35 mcg Daily Value. Other products you take may carry more.
| Source | Chromium | Compared with the label |
|---|---|---|
| Hawaiian Harmony, per dropperful | 7 mcg | 1 times |
| A multivitamin | 35 to 120 mcg | 5 to about 17 times |
| A chromium-only supplement | 200 to 500 mcg | About 29 to 71 times |
The sheet sets no Tolerable Upper Intake Level for chromium. That is not a licence to stack products. Tell your doctor about every item with chromium in it, so they see the full daily total.

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Are there food and drink Hawaiian Harmony interactions to know?
Two stand out in the sources this site cites. The first is timing with green tea. Drugs.com's monograph notes that green tea extract should not be taken on an empty stomach because plasma EGCG rises fivefold in the fasted state. The label gives no time of day, so taking the dropperful with food is a reasonable habit to discuss with your doctor.
The second is licorice. The blend names a salt of glycyrrhizin, the compound in licorice root. Its ceiling is 0.86 mg. The suggested acceptable daily intake is 0.2 mg for each kg of body weight, which is about 14 mg for a 70 kg adult, so the drops sit comfortably under it. The monograph adds that as little as 50 g a day of licorice itself has produced a blood pressure effect. If you eat a lot of licorice sweets or drink licorice tea, mention it.
What about Hawaiian Harmony interactions with other supplements?
Several names in the blend are also sold on their own: L-arginine, L-carnitine, beta alanine, L-glutamine, L-tyrosine, L-tryptophan, GABA, green tea and ginseng. If another product lists the same names, you cannot add the two amounts, because the amount here is not printed.
What you can do is list your supplements, put them side by side and show the list to a pharmacist. The published daily amounts for these names on this site run from 84 mg for green tea and 100 mg for ginseng up to several grams for the amino acids, while each name here has a ceiling of 2.21 mg or less. A ceiling is not an amount, though, so a pharmacist should judge your case.
For medicines, read the post on Hawaiian Harmony with medications. It sets out what to bring and which questions to ask.
Which Hawaiian Harmony interactions happen at home with pets and children?
The sweetener xylitol is in the other ingredients, and the FDA says it can cause a rapid, profound drop in blood sugar in dogs within 10 to 60 minutes. The amount in the bottle is not declared. Keep the bottle in a closed cupboard and never leave the dropper out.
The label also says to keep the bottle out of the reach of children. If a child or a pet gets into it, call a doctor or a vet at once. See who it is for for the label's full list of cautions.
Frequently asked questions
Does Hawaiian Harmony contain caffeine?
It names guarana and green tea, both caffeine sources. The caffeine amount is not declared.
Can I take it with my multivitamin?
Ask your doctor. A multivitamin has 35 to 120 mcg of chromium, and the drops add 7 mcg.
Is the licorice compound a problem?
At its ceiling of 0.86 mg it is well under the suggested daily limit of about 14 mg for a 70 kg adult. Mention heavy licorice use to your doctor.
Should I take it on an empty stomach?
The label gives no time of day. Green tea extract should not be taken on an empty stomach, so ask your doctor about taking it with food.
Can it interact with my prescription?
It cannot be checked against a dose, because no blend amounts are printed. Ask a pharmacist with the bottle in hand.
Why is xylitol listed as an interaction?
It is a sweetener that is dangerous to dogs. Keep the bottle out of reach of pets and children.
Our view
Most Hawaiian Harmony interactions are small and easy to see once you list them: some caffeine, some chromium that adds up across products, a licorice compound well under its limit, a timing note for green tea and a real risk for dogs.
The one you cannot check is a medicine interaction, because the label prints no single amounts. For that, you need a pharmacist, the bottle and a full list.
Sources
- Guarana: clinical monographDrugs.com natural products databaseDoses of 75 mg to 1,000 mg daily have been used in limited trials; guarana seed is 3% to more than 5% caffeine by dry weight.
- Green Tea: clinical monographDrugs.com natural products databaseGreen tea extract should not be taken on an empty stomach, because plasma EGCG rises fivefold in the fasted state.
- Licorice: clinical monographDrugs.com natural products databaseSuggested acceptable daily intake for glycyrrhizin is 0.2 mg per kg a day; as little as 50 g a day of licorice has produced blood pressure effects.
- Chromium: Fact Sheet for Health ProfessionalsNIH Office of Dietary SupplementsDaily Value 35 mcg; chromium-only supplements typically provide 200 to 500 mcg; no Tolerable Upper Intake Level was established; insufficient rationale to recommend chromium for type 2 diabetes.
- Paws Off Xylitol; It's Dangerous for DogsU.S. Food and Drug AdministrationXylitol appears in many products including dietary supplements; in dogs it may cause a rapid drop in blood sugar within 10 to 60 minutes.
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USA Authorized Hawaiian Harmony Retailer · United States · not medical advice